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Krystyna Michalak Selected Research

Phenothiazines

2/2019The Combined Use of Phenothiazines and Statins Strongly Affects Doxorubicin-Resistance, Apoptosis, and Cox-2 Activity in Colon Cancer Cells.
10/2018Increased lipid peroxidation, apoptosis and selective cytotoxicity in colon cancer cell line LoVo and its doxorubicin-resistant subline LoVo/Dx in the presence of newly synthesized phenothiazine derivatives.
1/2003Antimicrobial activity of N-acylphenothiazines and their influence on lipid model membranes and erythrocyte membranes.

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Krystyna Michalak Research Topics

Disease

22Neoplasms (Cancer)
04/2021 - 09/2002
8Colonic Neoplasms (Colon Cancer)
04/2020 - 10/2010
7Adenocarcinoma
04/2019 - 10/2010
3Melanoma (Melanoma, Malignant)
04/2021 - 05/2015
3Lymphoma (Lymphomas)
11/2009 - 09/2002
2B-Cell Chronic Lymphocytic Leukemia (Chronic Lymphocytic Leukemia)
01/2019 - 05/2015
2Breast Neoplasms (Breast Cancer)
11/2009 - 01/2009
2Hemolysis
01/2003 - 01/2002
1Atherosclerosis
04/2021
1Hypercholesterolemia
04/2021
1Lung Neoplasms (Lung Cancer)
04/2021
1B-Cell Lymphoma (Lymphoma, B Cell)
02/2019
1Cardiovascular Diseases (Cardiovascular Disease)
01/2019
1Infections
01/2019
1Carcinoma (Carcinomatosis)
05/2016
1Sarcoma (Soft Tissue Sarcoma)
01/2005
1Communicable Diseases (Infectious Diseases)
09/2003

Drug/Important Bio-Agent (IBA)

9Doxorubicin (Adriamycin)FDA LinkGeneric
04/2020 - 10/2010
6FlavonoidsIBA
01/2019 - 01/2009
6Member 1 Subfamily B ATP Binding Cassette TransporterIBA
05/2016 - 09/2002
5Pharmaceutical PreparationsIBA
01/2019 - 01/2005
5multidrug resistance-associated protein 1IBA
10/2012 - 12/2005
4Simvastatin (Zocor)FDA LinkGeneric
04/2021 - 01/2019
4phenothiazineIBA
04/2019 - 09/2002
4Proteins (Proteins, Gene)FDA Link
04/2019 - 09/2002
3Voltage-Gated Potassium Channels (Voltage-Gated Potassium Channel)IBA
04/2021 - 05/2015
3Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA
04/2021 - 01/2019
3PhenothiazinesIBA
02/2019 - 01/2003
3StilbenesIBA
05/2015 - 11/2010
3Adenosine Triphosphate (ATP)IBA
10/2012 - 12/2005
3ATP-Binding Cassette Transporters (ABC Transporters)IBA
10/2012 - 11/2009
2mevastatin (CS 500)IBA
04/2021 - 01/2019
2AntioxidantsIBA
01/2014 - 09/2009
2Biological ProductsIBA
01/2014 - 09/2009
28-prenylnaringeninIBA
12/2012 - 10/2010
2Phytoestrogens (Phytoestrogen)IBA
12/2012 - 10/2010
2PolyphenolsIBA
10/2012 - 09/2009
2ResveratrolIBA
11/2010 - 09/2009
23,3',4,5'-tetrahydroxystilbeneIBA
11/2010 - 09/2009
1Pravastatin (Pravachol)FDA LinkGeneric
04/2021
1SILA-409IBA
04/2020
1Organosilicon CompoundsIBA
04/2020
1TheobromineIBA
04/2019
1Cyclooxygenase 2 (Cyclooxygenase-2)IBA
02/2019
1bcl-2-Associated X Protein (bcl 2 Associated X Protein)IBA
02/2019
1Caspase 3 (Caspase-3)IBA
02/2019
13-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA)IBA
01/2019
1Mevalonic Acid (Mevalonate)IBA
01/2019
1CholesterolIBA
01/2019
1Oxidoreductases (Dehydrogenase)IBA
01/2019
1Polycyclic CompoundsIBA
01/2019
1MicroRNAs (MicroRNA)IBA
01/2019
1EnzymesIBA
01/2019
1acacetinIBA
12/2018
1chrysinIBA
12/2018
1Reactive Oxygen Species (Oxygen Radicals)IBA
10/2018
1LuteolinIBA
04/2017
1baicaleinIBA
04/2017
1FlavonesIBA
04/2017
1CoumarinsIBA
05/2016
1DiterpenesIBA
05/2016
1PhytochemicalsIBA
05/2015
1naringeninIBA
11/2012
1tangeretinIBA
11/2012
1aromadedrin (dihydrokaempferol)IBA
11/2012
1Antineoplastic Agents (Antineoplastics)IBA
10/2012
1Subfamily B ATP Binding Cassette TransporterIBA
10/2012
1Rhodamine 123IBA
11/2009
1phenoxazineIBA
01/2006
1Multidrug Resistance-Associated ProteinsIBA
12/2005
1MaleatesIBA
09/2002
1acylphenothiazineIBA
09/2002
1Thioridazine (Mellaril)FDA LinkGeneric
01/2002

Therapy/Procedure

3Therapeutics
04/2021 - 05/2015
3Drug Therapy (Chemotherapy)
04/2020 - 09/2003
1Chemoprevention
04/2017